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Alizapride hydrochloride

Catalog No. T2574 CAS 59338-87-3

Synonyms: Alizapride HCl

Alizapride hydrochloride (Alizapride HCl) is a dopamine receptor antagonist used for the treatment of nausea and vomiting.

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Alizapride hydrochloride Chemical Structure

Alizapride hydrochloride, CAS 59338-87-3

Pack Size	Availability	Price/USD
25 mg	In stock	$ 48.00
50 mg	In stock	$ 71.00
100 mg	In stock	$ 113.00
200 mg	In stock	$ 168.00
500 mg	In stock	$ 283.00
1 mL * 10 mM (in DMSO)	In stock	$ 39.00

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Purity: 99.71%

Purity: 99.48%

Biological Description

Chemical Properties

Storage & Solubility Information

Description	Alizapride hydrochloride (Alizapride HCl) is a dopamine receptor antagonist used for the treatment of nausea and vomiting.
In vitro	Intravenous administration of 5 mg/kg Alizapride in rats effectively counteracts the reduction in gastrointestinal motility induced by the given dose of Apomorphine. Alizapride exhibits low toxicity in mice and rats, particularly when administered extragastrically. Following oral or extragastric administration, Alizapride is primarily excreted in its unmodified form; however, approximately 25% of Alizapride undergoes metabolic transformation before excretion.
In vivo	Alizapride contains an N-allyl moiety, which may undergo N-deallylation and/or epoxidation, potentially leading to the formation of chemically reactive metabolites.

Synonyms	Alizapride HCl
Molecular Weight	351.83
Formula	C16H21N5O2·HCl
CAS No.	59338-87-3

Storage

Powder: -20°C for 3 years | In solvent: -80°C for 1 year

Solubility Information

H2O: 50 mg/mL (142.11 mM), Sonication is recommended.

Ethanol: < 1 mg/mL (insoluble or slightly soluble)

DMSO: 39 mg/mL (110.8 mM)

References and Literature

1. Aprile S, et al. J Mass Spectro, 2012, 47(6), 737-750. 2. Dhasmana KM, et al. Pharmacol Res, 1993, 27(4), 335-347.

Related compound libraries

This product is contained In the following compound libraries：

Anti-Neurodegenerative Disease Compound Library Drug Repurposing Compound Library Anti-Cancer Approved Drug Library Membrane Protein-targeted Compound Library Anti-Cancer Drug Library Inhibitor Library GPCR Compound Library ReFRAME Related Library Anti-Obesity Compound Library Bioactive Compounds Library Max

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Related compounds with same targets

PF-00217830 Pimethixene Hexamethonium Bromide Prochlorperazine Maleate Perospirone hydrochloride Levosulpiride PD 168568 dihydrochloride NRA-0160

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Method for preparing DMSO master liquid: mg drug pre-dissolved in μL DMSO (Master liquid concentration mg/mL)，Please contact us first if the concentration exceeds the DMSO solubility of the batch of drug.

Method for preparing in vivo formulation：Take μL DMSO master liquid, next add μL PEG300， mix and clarify, next add μL Tween 80，mix and clarify, next add μL ddH₂O, mix and clarify.

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Please see Inhibitor Handling Instructions for more frequently ask questions. Topics include: how to prepare stock solutions, how to store products, and cautions on cell-based assays & animal experiments, etc.

Keywords

Alizapride hydrochloride 59338-87-3 GPCR/G Protein Neuroscience Dopamine Receptor inhibit Alizapride Alizapride Hydrochloride Alizapride HCl Inhibitor inhibitor

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